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ACROBiosystems社 Tau-targeted Therapies for Alzheimer's Disease

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Products Support Insights Resources

 

In the search for effective Alzheimer's disease (AD) treatments, tau-targeted therapies includes reducing tau expression, targeting tau protein modifications, inhibiting tau aggregation, stabilizing microtubules, and employing active and passive immunotherapies. These therapies aim to interrupt the pathological processes triggered by tau protein, ultimately striving to slow or halt the progression of AD.

 

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https://doi.org/10.1038/s41582-023-00883-2

Tau-related therapeutic targets

 

To support research into the diagnosis and treatment of AD, ACROBiosystems provides you with diverse Tau recombinant proteins and Tau-441 Pre-formed Fibrils.

 

Verification Data

 

Bioactivity-ELISA

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Immobilized Human Tau-441 (P301L), His Tag (Cat. No. TAU-H5144) at 5 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.5-8 ng/mL (QC tested).

 

Protocol

Bioactivity-ThT Assay

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Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time when tau K18 monomers are combined with Human Tau-441 K18 Pre-formed Fibrils Protein, His Tag (Cat. No. TAU-H5146) (Routinely tested).

 

Protocol

 

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