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SinoBiological社 Antibodies for Influenza Antigen Test

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Influenza viral nucleoprotein (NP) is a structural protein that plays a critical role in virus replication and host adaptation. Antibodies targeting NP proteins are commonly used for immunodetection of influenza viruses in various assays, including ELISA, lateral flow assay (LFA), and direct fluorescent antibody tests. These assays can be used in both research and clinical diagnostics. Due to the high frequency of antigenic drift or shift among different influenza strains, broad-spectrum influenza antibodies are particularly desired for flu diagnostics.
Sino Biological has identified six Pan antibody pairs against the NP protein of Influenza A and Influenza B, respectively. These matched pairs have been validated in the sandwich ELISA assay with high sensitivity (pg level). They also demonstrate broad reactivity against a large cohort of flu strains.
 
Antibody Pairs for Pan Influenza A NP Detection   Antibody Pairs for Pan Influenza B NP Detection
Pair No. Capture Ab Detection Ab
PanA-1 40205-MM16 40208-R014
PanA-2 40205-R063 40205-MM18
PanA-3 40208-R117 40205-MM18
 
Pair No. Capture Ab Detection Ab
PanB-1 40438-R004 40438-MM10
PanB-2 40438-R036 40438-MM10
PanB-3 40438-MM05 40438-R036
High Sensitivity (pg level)
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Broad Spectrum and High Specificity
These antibody pairs can detect a broad spectrum of strains within the target subtype, without any cross-reactivity with the other subtypes.
24 kinds of influenza antigens from A or B have been tested by ELISA assay
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The Aforementioned Antigens:
B-1: 40783-V08B (B, B/Brisbane/60/2008) A-8: 40774-V08B (H1N1, A/Victoria/2570/2019 | A/Wisconsin/588/2019)
B-2: 40782-V08B (B, B/Colorado/06/2017) A-9: 40033-V08B (H2N2, A/Ann Arbor/6/1960)
B-3: 40438-V08B (B, B/Florida/4/2006) A-10: 40207-V08B (H3N2, A/Aichi/2/1968)
B-4: 40500-V08B (B, B/Phuket/3073/2013) A-11: 40778-V08B (H3N2, A/Cambodia/e0826360/2020 (H3N2)-like)
B-5: 40755-V08B (B, B/Washington/02/2019) A-12: 40208-V08B (H3N2, A/Hong Kong/1/1968)
A-1: 40204-V08B (H1N1, A/Brevig Mission/1/1918) A-13: 40753-V08B (H3N2, A/Hong Kong/2671/2019)
A-2: 40776-V08B (H1N1, A/Brisbane/02/2018) A-14: 40754-V08B (H3N2, A/Hong Kong/45/2019)
A-3: 40205-V08B (H1N1, A/California/07/2009) A-15: 40781-V08B (H3N2, A/Hong Kong/4801/2014 )
A-4: 40723-V08B (H1N1, A/Guangdong-Maonan/SWL1536/2019) A-16: 40779-V08B (H3N2, A/Kansas/14/2017)
A-5: 40724-V08B (H1N1, A/Hawaii/70/2019) A-17: 40499-V08B (H3N2, A/Switzerland/9715293/2013)
A-6: 40777-V08B (H1N1, A/Michigan/45/2015) A-18: 40110-V08B (H7N9, A/Anhui/1-BALF_RG6/2013)
A-7: 11675-V08B
(H1N1, A/Puerto Rico/8/34/Mount Sinai)
A-19: 40111-V08B (H7N9, A/Shanghai/2/2013)
 
High Binding Affinity
The binding affinity between immobilized Influenza B NP protein (Cat#: 40500-V08B) with the anti-NP antibody (Cat#: 40438-R036) in BLI assay. The binding affinity between immobilized Influenza A NP protein (Cat#: 40774-V08B) with the anti-NP antibody (Cat#: 40205-R063) in BLI assay.
 
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Antibody Cocktail Can Successfully Detect both A and B Type Flu
The combination of A and B antibody pairs can allow detection of both subtypes.
High Production Quality
Our products and processes are ISO13485 certified. The purity of these antibodies is >95% as assessed by SEC-HPLC.
 
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Other Pan Influenza NP Antibodies
16 Pan Influenza A or B Nucleoprotein antibodies have been developed and validated by ELISA and WB assays.
Pan Influenza A NP Antibodies
 
40208-MM03   40208-R014   40208-MM04
 
40208-R010   40208-R061   40208-R113
 
40208-R117   40205-MM16   40205-MM18
 
40205-R063        
 
Pan Influenza B NP Antibodies
 
40438-MM05   40438-R016   40438-MM09
 
40438-R036   40438-R004   40438-MM10
 
 

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