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SinoBiological社 Recombinant Antigens for 2022-2023 Influenza Vaccine Strains



Vaccination is the most effective way to prevent flu infection. Each year, several different flu strains are selected as vaccine candidates based on surveillance data of the recent isolates and the performance of the vaccines from the previous season. In recent decades, most influenza vaccines are trivalent or quadrivalent, composed of one H1N1, one H3N2, and either one or two type B viruses (Yamagata and Victoria lineage).
Sino Biological offers recombinant ?u antigen products under its ProVir™ viral antigen collection. The product line covers Hemagglutinin (HA), Neuraminidase (NA), and Nucleoprotein (NP) proteins from all WHO-recommended vaccine strains in recent years. These antigens can be used to analyze vaccine-induced antibody response. In addition, Sino Biological also develops a large collection of monoclonal antibodies against the ?u antigens. These reagents can help facilitate relevant assay development.
Flu Antigens for 2022-2023 Vaccine Strains
A/Victoria/2570/2019 (H1N1)   A/Wisconsin/588/2019 (H1N1)
Recommended for Egg-based (quadrivalent, trivalent) Vaccine Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine
HA: 40787-V08H, 40787-V08H1 HA: 40787-V08H, 40787-V08H1
NA: 40785-V08B NA: 40785-V08B
NP: 40774-V08B NP: 40774-V08B
B/Phuket/3073/2013   A/Darwin/9/2021 (H3N2)
Recommended for Egg-based (quadrivalent, trivalent) Vaccine Recommended for Egg-based (quadrivalent, trivalent) Vaccine
HA: 40498-V08B HA: 40859-V08H (pre-order)
40859-V08B (pre-order)
NA: 40502-V07B NA: 40860-V08B (pre-order)
NP: 40500-V08B NP: 40858-V08B (pre-order)
B/Austria/1359417/2021 (B/Victoria lineage)   A/Darwin/6/2021 (H3N2)
Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine
HA: 40862-V08H (pre-order) HA: 40868-V08H (pre-order)
40862-V08B (pre-order) 40868-V08B (pre-order)
NA: 40863-V08B (pre-order) NA: 40869-V08B (pre-order)
NP: 40861-V08B (pre-order) NP: 40858-V08B (pre-order)
More Recombinant Antigens for Vaccine Strains
Strains HA NA NP Year
A/Brisbane/02/2018 (H1N1) 40719-V08H 40767-V08B 40776-V08B 2019-2020
A/California/7/2009 (H1N1) 11085-V08B   40205-V08B 2016-2017, 2015-2016
A/Cambodia/e0826360/2020 (H3N2) 40789-V08H
40784-V08B 40778-V08B 2021-2022
A/Guangdong-Maonan/SWL1536/2019 (H1N1) 40717-V08H   40723-V08B 2020-2021
A/Hawaii/70/2019 (H1N1) 40717-V08H   40724-V08B 2020-2021
A/Hong Kong/2671/2019 (H3N2) 40721-V08H   40753-V08B 2020-2021
A/Hong Kong/45/2019 (H3N2) 40765-V08H   40754-V08B 2020-2021
A/Hong Kong/4801/2014 (H3N2) 40555-V08B 40569-V08B 40781-V08B 2017-2018, 2016-2017
A/Kansas/14/2017 (H3N2) 40720-V08H 40766-V08B 40779-V08B 2019-2020
A/Michigan/45/2015 (H1N1) 40567-V08H1 40568-V08B 40777-V08B 2018-2019, 2017-2018
A/Singapore/INFIMH-16-0019/2016 (H3N2) 40580-V08H   40779-V08B 2018-2019
A/Switzerland/9715293/2013 (H3N2) 40497-V08B   40499-V08B 2015-2016
A/Victoria/2570/2019 (H1N1) 40787-V08H
40785-V08B 40774-V08B 2021-2022
A/Wisconsin/588/2019 (H1N1) 40787-V08H
40785-V08B 40774-V08B 2021-2022
B/Brisbane/60/2008 40016-V08B 40203-VNAHC 40783-V08B 2017-2018, 2016-2017, 2015-2016
B/Colorado/06/2017 40581-V08H   40782-V08B 2019-2020, 2018-2019
B/Phuket/3073/2013 40498-V08B 40502-V07B 40500-V08B 2021-2022, 2020-2021, 2019-2020, 2018-2019, 2017-2018, 2016-2017, 2015-2016
B/Washington/02/2019 40722-V08H 40790-V08B 40755-V08B 2021-2022, 2020-2021

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