With wave upon wave of the successful application in drug combination and bispecific antibody trials, CTLA-4 has attracted more and more attentions from scientists.

CTLA-4 protein, also named CD152 protein, is a kind of T cell receptor which is active as a
homodimer.

Fig 1. Structure of CTLA-4 dimer

ACROBiosystems has developed an active homodimer CTLA-4 protein (Cat.# CT4-H52H9) with high purity over 90%, which is verified by SEC-MALS. In addition, ACROBiosystems also developed a series of CTLA-4 proteins with more than 5 species (human, mouse, cynomolgus, etc.) and 5 tags (Fc, His, AvitagTM, etc.) to support your antibody drug development.

Product list

Assay data

Fig 2. The purity of Human CTLA-4, His Tag (Cat. No. CT4-H52H9) was more than 90% and the molecular weight of this protein is around 45-60 kDa verified by SEC-MALS.

Fig 3. Immobilized Human B7-1, Fc Tag (HPLC-verified) (Cat. No. bind Human CTLA-4, His Tag (Cat. No. CT4-H52H9) at 2 μg/mL (100 μL/well) can bind Human CTLA-4, His Tag (Cat. No. CT4-H52H9) with a linear range of 0.1-2 ng/mL.

Click to learn more targets for bispecific antibodies:

                              CD3                            CTLA-4                              CD47

                              CD20                           CD19                                PD-L1

We also developed some ELISA assay kits for Anti-CTLA-4 h-mAb in serums, click to learn more.

 Cat.No.                                           Product description

ECH-V1              ELISA Assay Kit for Anti-CTLA-4 h-mAb in Human Serum

ECM-V1              ELISA Assay Kit for Anti-CTLA-4 h-mAb in Human Serum

 
ECC-V1              ELISA Assay Kit for Anti-CTLA-4 h-mAb in Human Serum