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ACROBiosystems社 ACRO Weekly - The latest news for you



Therapeutic Antibodies Solutions


The latest products & news from ACROBiosystems


Inspiring Protein Targets

G Protein-coupled Receptors (GPCRs)


G protein-coupled receptors (GPCRs) are the largest family of membrane proteins and have also been implicated in a large number of diseases, such as type 2 diabetes mellitus (T2DM), obesity, depression, cancer, and many others. Therefore, GPCRs have become the most successful drug targets for the treatment of a variety of diseases.



ACROBiosystems has launched several full-length transmembrane proteins including PAR2, CXCR6, GPRC5B, and CXCR3 based on a multi-pass transmembrane proteins development technology platform to accelerate GPCRs targeted drug development!


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Comprehensive Cytokines Targets Collection


Cytokines are soluble signaling proteins with a wide range of biological activities. An imbalance in the regulation of cytokine expression is associated with the occurrence and development of many diseases and has some clinical applications in respiratory diseases, infections, autoimmune diseases, and tumors.

Neuroscience Solutions


The latest news from Aeuro, an ACROBiosystems brand.


Establishing a more accurate neurodegenerative disease model 


A hallmark of neurodegenerative diseases is the aggregation of certain proteins in patient brains due to misfolding, deposition, and entanglement that leads to neurodegeneration. Due to the varying mechanisms that lead to protein aggregation, building a reliable and accurate disease model to understand pathogenesis is challenging. Induced PFFs are designed to mimic naturally occurring pathological states and processes.


To help provide you with better tools for neurodegenerative disease modeling, we offer both Tau-441 and α-syn PFFs that closely resemble filaments found in vivo.



α-syn filaments

ACRO α-syn PFFs

Cat. No. ALN-H51H4
Alpha-synuclein filaments labeled using anti-α-synuclein antibody PER1 derived from the cingulate cortex of patients afflicted with dementia.1 Transmission electron microscopy (TEM) of alpha-synuclein-preformed fibrils. Fibril structure is visible on negative stain TEM images.


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Solutions for electrophysiology recordings


Electrophysiology recordings are an essential part of neuroscience research, helping us elucidate the different field potentials within different brain regions and the flow of electrical signals between neurons. Electrophysiological recordings are critical for analyzing different neural circuit functions and their association with neurodegenerative diseases.

Read our insight article on Pre-formed Fibrils!

Learn about:

  • Current neurodegenerative disease models
  • Formation of pre-formed fibrils
  • Research applications of PFFs
ACRO_Weekly_9.jpgClick to read now! >> 

ADC Solutions


The latest products & news from ACROBiosystems


Inspiring Protein Targets

Trophoblast Antigen 2 (TROP-2)


With the expansion of the TROP-2 targeting pipeline, companion diagnostics are critical in evaluating the best therapy for patients. This includes immunohistochemistry (IHC), which is the classical method for predicting tumor response to target-specific therapies. Explore our IHC antibodies, including TROP-2 below!


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Free sample of Immunocytochemistry Antibody


We are offering a free sample of the top-quality immunocytochemistry antibody for a limited time, don't miss out on the opportunity the request a trial pack!


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1Spillantini M., Crowther R., et al. Proc. Natl. Acad. Sci. Vol. 95, pp. 6469 – 6473.

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