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ACROBiosystems社 CD19 a validated therapeutic target for B-cell malignancies


CD19a validated therapeutic target for B-cell malignancies


Product Features

 Biotinylated, fluorescent-labeled and unconjugated CD19 are available.

 High bioactivity verified by FACS, SPR and ELISA with protocol offered for free.

 Suitable for detection of anti-CD19 CAR expression and antibody drug screening.

CD19_a_validated_therapeutic_target_for_B-cell_malignancies_3.jpg Detection of Anti-CD19 CAR Expression by FACS

 1e6 of the anti-CD19 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human CD19 (20-291), His Tag (Cat. No. CD9-HP2H3). PE Streptavidin was used as negative control (QC tested)

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High Affinity Verified by SPR

Biotinylated Human CD19 (20-291), His,Avitag (Cat. No. CD9-H82E9) captured on Biotin CAP - Series S sensor Chip can bind FMC63 MAb (mouse lgG2a) with an affinity constant of 0.255 nM as determined in a SPR assay (Biacore 8K) (QC tested)

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