Discover more inspirational targets

Transmembrane proteins (TPs) play crucial physiological roles in vivo and are the major category of drug targets for pharmaceuticals. The research on TPs is a significant part of drug discovery. ACROBiosystems has specially set up three technology platforms to address the structural complexity and high activity of Multi-pass TPs including CD20, Claudin18.2, CD133, GPRC5D, CCR5, and CCR8 to facilitate drug development and mechanism studies.

 Explore more about the structures and functions

CD20 exists as a dimer in a crystal structure and multiple reports indicate that its two extracellular loops form epitopes which are strong antibody/CAR-T targets. ACROBiosystems made efforts to purify and stabilize full-length CD20 successfully. The protein performed very well in ELISA assays using Rituximab and Obinutuzumab. 

 Learn more efficient assays for quality control

>> Efficient tools to save half of your time costs in flow cytometry 

Evaluating CAR expression is an essential step in the production of CAR-T cells. Fluorescent-labeled proteins, with high specificity and minimal background staining, can be powerful tools for the detection of CAR expression by flow cytometry. By using featured site-specific conjugation technology, ACROBiosystems has developed an exclusive collection of fluorescent-labeled proteins with high bioactivity verified by flow cytometry. Protocols are offered for free, which can help you enhance the development cycle.

SARS-CoV-2 Variants-specific

ELISA kits

ELISA Assay Kits for Quantitative

Analysis of mAb in serum