ACROBiosystems社 From target to QC assay, for Biopharma industry
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From target to QC assay, for Biopharma industry
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>> Solutions for Full-length Multi-pass Transmembrane Proteins
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Transmembrane proteins (TPs) play crucial physiological roles in vivo and are the major category of drug targets for pharmaceuticals. The research on TPs is a significant part of drug discovery. ACROBiosystems has specially set up three technology platforms to address the structural complexity and high activity of Multi-pass TPs including CD20, Claudin18.2, CD133, GPRC5D, CCR5, and CCR8 to facilitate drug development and mechanism studies.
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>> Top 10 targets from ACROBiosystems:
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Explore more about the structures and functions
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CD20 exists as a dimer in a crystal structure and multiple reports indicate that its two extracellular loops form epitopes which are strong antibody/CAR-T targets. ACROBiosystems made efforts to purify and stabilize full-length CD20 successfully. The protein performed very well in ELISA assays using Rituximab and Obinutuzumab.
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>> Featured proteins with authentic structures from ACROBiosystems:
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Learn more efficient assays for quality control
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Evaluating CAR expression is an essential step in the production of CAR-T cells. Fluorescent-labeled proteins, with high specificity and minimal background staining, can be powerful tools for the detection of CAR expression by flow cytometry. By using featured site-specific conjugation technology, ACROBiosystems has developed an exclusive collection of fluorescent-labeled proteins with high bioactivity verified by flow cytometry. Protocols are offered for free, which can help you enhance the development cycle.
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>> Convenient tools from ACROBiosystems: |
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High-quality CD3 Protein Plays Crucial Role in Anti-CD3 Bispecific Antibodies Development
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Engineering recombinant immune checkpoint proteins for antibody drug development
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