Fount of Information

AcroBiosystems社 From target to QC assay, for Biopharma industry

この製品に関するご意見・ご照会・お問合せはこちら

Acro_logo.png

Products

Support

Scientific Talk

 COVID-19 R&D

About Us

 

From target to QC assay, for Biopharma industry

 

 Discover more inspirational targets

 

 


  

>> Solutions for Full-length Multi-pass Transmembrane Proteins

Solution_for.jpg

Transmembrane proteins (TPs) play crucial physiological roles in vivo and are the major category of drug targets for pharmaceuticals. The research on TPs is a significant part of drug discovery. ACROBiosystems has specially set up three technology platforms to address the structural complexity and high activity of Multi-pass TPs including CD20, Claudin18.2, CD133, GPRC5D, CCR5, and CCR8 to facilitate drug development and mechanism studies.

 

Discover_more.PNG

 

>> Top 10 targets from ACROBiosystems:

 

CD19 HER2 PD-1 DLL3 BCMA
TIGIT CD47 PSMA EGF R GPC3

 Explore more about the structures and functions

 

 

>> How the two extracellular loops of CD20 works in binding with antibody drugs?

 

loops_of_CD20.jpg

CD20 exists as a dimer in a crystal structure and multiple reports indicate that its two extracellular loops form epitopes which are strong antibody/CAR-T targets. ACROBiosystems made efforts to purify and stabilize full-length CD20 successfully. The protein performed very well in ELISA assays using Rituximab and Obinutuzumab. 

Explore_more.PNG

  

>> Featured proteins with authentic structures from ACROBiosystems:

 

CD3E&CD3D heterodimer IL-2R complex Spike trimer
MALS verified trimeric TNFSF CD28 homodimer

 Learn more efficient assays for quality control

 

 

>> Efficient tools to save half of your time costs in flow cytometry 

 

efficient_tools.jpg

Evaluating CAR expression is an essential step in the production of CAR-T cells. Fluorescent-labeled proteins, with high specificity and minimal background staining, can be powerful tools for the detection of CAR expression by flow cytometry. By using featured site-specific conjugation technology, ACROBiosystems has developed an exclusive collection of fluorescent-labeled proteins with high bioactivity verified by flow cytometry. Protocols are offered for free, which can help you enhance the development cycle.

 

Learn_more.PNG

>> Convenient tools from ACROBiosystems:
 Pre-coupling magnetic beads 

SARS-CoV-2 Variants-specific

ELISA kits

 Inhibitor Screening Kits 

ELISA Assay Kits for Quantitative

Analysis of mAb in serum


 
Resources

 

Resources.png

High-quality CD3 Protein Plays Crucial Role in Anti-CD3 Bispecific Antibodies Development

 

Request_for_poster.PNG


 
immune_checkpoint.jpg

Engineering recombinant immune checkpoint proteins for antibody drug development

 

Request_for_poster.PNG



Fount of Information は、新商品、新規取扱メーカーなどの情報をいち早く紹介するコンテンツです。情報発信のスピードを重視しているコンテンツのため、現時点で法規制や取り扱いを確認できていない商品、定価を設定できていない商品があります。ご要望やご照会を受けた商品について、法令整備や在庫の充実を図ります。