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ACROBiosystems社 Isolated antibodies in SARS-CoV-2 infected patients have potential to treat COVID-19

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Isolated antibodies in SARS-CoV-2 infected patients have potential to treat COVID-19

 

Recently a team of Chinese scientists published a research paper1 on bioRxiv, the preprint server for Biology, reporting the isolation and characterization of mAbs derived from single B cells of eight SARS-CoV-2 infected individuals. The highlights of this study are summarized here:

 

1) Serial dilutions of plasma samples from eight SARS-CoV-2 infected subjects were analyzed for binding to RBDs from SARS-CoV-2, SARS-CoV and MERS-CoV. The plasma samples showed binding activity to SARS-CoV-2 RBD, while no cross-reactivity was detected against SARS-CoV RBD and MERS-CoV RBD. The results suggest that the RBD-based antibody response is viral species-specific (Fig 1).

 

Fig1_Analyses_of_plasma_responses specific_to_SARS-CoV-2.png

 Fig 1. Analyses of plasma responses specific to SARS-CoV-2

 

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