ACROBiosystems社 Neutralization of N501Y mutant SARS-CoV-2
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Neutralization of N501Y mutant SARS-CoV-2 by BNT162b2 vaccine-elicited sera | |||||
Rapidly spreading variants of SARS-CoV-2 that have arisen in the United Kingdom and South Africa share the spike N501Y substitution, which is of particular concern because it is located in the viral receptor binding site for cell entry and increases binding to the receptor. |
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The results from an in vitro study conducted by the University of Texas Medical Branch (UTMB) and Pfizer shows the antibodies from people who have received the Comirnaty COVID-19 vaccine effectively neutralize SARS-CoV-2 with a key mutation that is also found in two highly transmissible strains. |
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List of SARS-CoV-2 Spike Mutants | |||||
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SPD-C52Hn | SARS-CoV-2 (COVID-19) S protein RBD (N501Y), His Tag | Preorder | |||
SPD-C52Hp | SARS-CoV-2 (COVID-19) S protein RBD (K417N, E484K, N501Y), His Tag | Preorder | |||
S1N-C52Hd | SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag | Preorder | |||
S1N-C52Hg | SARS-CoV-2 (COVID-19) S1 protein (N501Y), His Tag | Preorder | |||
S1N-C5256 | SARS-CoV-2 (COVID-19) S1 protein (D614G), His Tag | Preorder | |||
S1N-C52Hk | SARS-CoV-2 (COVID-19) S1 protein (HV69-70del, N501Y, D614G), His Tag | Preorder | |||
SPN-C52H6 | SARS-CoV-2 (COVID-19) S protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H), His Tag | Preorder | |||
>>> Click to find out more SARS-CoV-2 protein mutants If you have any customized inquiries or suggestions for SARS-CoV-2 (COVID-19) related product development, please click here. |
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Related Article: Positive Phase 1/2 Study Results of Pfizer COVID-19 mRNA Vaccine |
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