The establishment of reliable disease models is crucial for discovering the pathological mechanisms, evaluating the efficacy of therapeutic interventions, and assessing the safety of drug candidates. Pre-formed fibrils (PFFs) are in vitro formed active fibrils that have "seeding" activity and are capable of continuously recruiting soluble endogenous pathological proteins to form aggregates and finally induce neurodegenerative pathologies.

Aneuro is ACROBiosystems’ brand that focuses on the field of neuroscience. Tau-441 PFFs will be coming soon to support and accelerate the establishment of reliable neurodegenerative models.