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Three anti-IFN γ antibodies in ACRO’s “mAb Matrix”
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mAb Matrix
As a leading manufacturer of recombinant proteins and other critical reagents to support the development of target therapeutics, vaccines, and diagnostics, ACROBiosystems has established an antibody product line named "mAb matrix". There are diverse antibodies in mAb matrix including biological target antibodies, biomarker antibodies, receptor antibodies, cytokine antibodies (interleukin antibodies, chemokine antibodies), virus antibodies, small molecular inhibitors antibodies, diagnostic antibodies, process engineering antibodies, etc.
The "antibody matrix" series products are characterized with high-specific and high -sensitivity, and they are suitable for the methodology construction of both diagnosis and the entire process in the biopharmaceutical R&D, helping to accelerate the medicine R&D and commercial process.
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IFN-γ is the only member of the type II interferon family and is a soluble cytokine. From a biological perspective, IFN-γ is a multi-effect cytokine with antiviral, antitumor and immune regulation. Therefore, IFN-γ plays an important role in coordinating congenital and adaptive immune reactions.
The detection and monitoring of IFN-γ is particularly important in clinical practice. At present, the detection of IFN-γ is usually carried out by the method of antigen-antibody specific binding. ACROBiosystems has launched three human-mouse chimeric anti-IFN γ antibodies derived from different clones: they can specifically bind to Human IFN-γ; they have been verified to be suitable for the detection of IFN-γ by antibodies sandwich method.
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★High purity: greater than 95% as verified by SDS-PAGE
★High specificity: only specifically binds to IFN-γ, not to other cytokines (IL-2, IL-4, IL-6, IL-10, GM-CSF, TNF-alpha)
★High biological activity: the binding activity and affinity to IFN-γ are verified by ELISA, SPR and BLI
★High sensitivity: suitable for the detection of IFN-γ and the development of detection methods, the sensitivity can reach pg grade
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Monoclonal Anti-IFNγ antibody, Human IgG1 (13E6H4)，(Cat. No. IFN-M411)
 Immobilized ActiveMax® Human IFN-gamma, Tag Free (Cat. No. IFG-H4211) can bind Monoclonal Anti-IFNγ antibody, Human IgG1 (13E6H4) (Cat. No. IFN-M411) with a linear range of 0.09-1.56 ng/mL (QC tested). No cross-reactivity is detected with other human cytokines, including IL-2, IL-4, IL-6, IL-10, GM-CSF and TNF-alpha.
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Monoclonal Anti-IFNγ antibody, Human IgG1 (8C5F8)，(Cat. No. IFN-M412)
 Immobilized ActiveMax® Human IFN-gamma, Tag Free (Cat. No. IFG-H4211) can bind Monoclonal Anti-IFNγ antibody, Human IgG1 (8C5F8) (Cat. No. IFN-M412) with a linear range of 0.09-1.56 ng/mL (QC tested). No cross-reactivity is detected with other human cytokines, including IL-2, IL-4, IL-6, IL-10, GM-CSF and TNF-alpha.
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Monoclonal Anti-IFNγ antibody, Human IgG1 (13E6H6)，(Cat. No. IFN-M414)
 Immobilized ActiveMax® Human IFN-gamma, Tag Free (Cat. No. IFG-H4211) can bind Monoclonal Anti-IFNγ antibody, Human IgG1 (13E6H6) (Cat. No. IFN-M414) with a linear range of 0.07-0.63 ng/mL (QC tested). No cross-reactivity is detected with other human cytokines, including IL-2, IL-4, IL-6, IL-10, GM-CSF and TNF-alpha.
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We will launch other members of ACRO "mAb Matrix" in succession. If you have any needs or more development suggestions, don't hesitate to contact us.
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