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AcroBiosystems社 Overview of Fc Receptors: classification and functions

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Overview of Fc Receptors: classification and functions

 


 

The binding of the antibody Fc-hinge region to FcγRs has been shown to exert a profound impact on antibody function and efficacy. Based on the differences in structure, function, and affinity for IgG binding, Fc gamma receptors (FcγRs) are classified into three major groups: FcγRI/CD64, FcγRII/CD32 (FcγRIIA, FcγRIIB, and FcγRIIC) and FcγRIII/CD16 (FcγRIIIA and FcγRIIIB).

 

Fc.pngFc_Category.png*The above Fc Receptors are available in ACROBiosystems

 

This overview highlights the classification and functions of FcγRs in humans and mice to give you a clear perspective on Fc-FcγRs interactions, especially unique immune responses to IgG subclasses.

 

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