Alomone Labs社 TRPC1 and TRPC6: Driving Endotoxemic Cardiac Dysfunction

TRPC1 and TRPC6: Driving Endotoxemic Cardiac Dysfunction

Sepsis remains a critical healthcare issue that can lead to multiple organ failure, with heart complications being particularly deadly. New research published in Nature Communications explores how selectively 'switching off' TRPC1 and TRPC6 can prevent damaging inflammation and heart failure, paving the way for a potent new avenue of septic heart failure treatment.

New Products

Membrane Protein Immunodetection

Primary Antibodies:

Anti-CDNF Antibody

Cat #: ANT-027
Type: Polyclonal | Host: Rabbit | Applications: IF, IHC, WB, *ICC, *IP |

Reactivity: H, M

Anti-PMCA4 Antibody

Cat #: ACP-004
Type: Polyclonal | Host: Rabbit | Applications: IF, IHC, WB, *ICC, *IFC, *IP |

Reactivity: R, *M

Anti-CLC-7 (CLCN7) Antibody

Cat #: ACL-008
Type: Polyclonal | Host: Rabbit | Applications: WB, *ICC, *IHC, *IP |

Reactivity: M, R, *H

Anti-GPR68 (OGR1) (extracellular) Antibody

Cat #: #AGR-042
Type: Polyclonal | Host: Rabbit | Applications: IFC, LCI, WB, *ICC, *IHC, *IP |

Reactivity: H, M, R

Antibodies for Live Cell Direct Flow Cytometry:

Anti-Plexin-A1 (extracellular)-FITC Antibody

Cat #: APR-081-F
Type: Polyclonal | Host: Rabbit | Applications: FC, LCI, *ICC | Reactivity: H, M, R

Anti-Human PAR1 (F2R) (extracellular)-FITC Antibody

Cat #: APR-031-F
Type: Polyclonal | Host: Rabbit | Applications: FC, LCI, *ICC | Reactivity: H

Ion Channel Pharmacology

Small Organic Molecules:

CNS-1102

Cat #: C-305
Type: Antagonists | Source: Synthetic | MW: 339.86 |

Target: NMDA receptors

Ro 8-4304 hydrochloride

Cat #: R-165
Type: Antagonists | Source: Synthetic | MW: 406.88 |

Target: NMDA receptors

PD-160725 2-hydroxyethanesulfonate

Cat #: P-280
Type: Antagonists | Source: Synthetic | MW: 444.46 |

Target: AMPA receptors

(S)-AMPA

Cat #: A-267
Type: Agonists | Source: Synthetic | MW: 186.17 |

Target: AMPA receptors

Why Alomone Labs?

Because we've been producing and validating membrane protein molecular tools in-house for decades.

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