Biotium社 Move Past Annexin V -- Try NucView® for Real-Time Apoptosis Monitoring.
Monitor apoptosis in real-time by flow cytometry or microscopy with NucView® Caspase-3 Substrates. Validated in hundreds of publications and over a hundred cell types, NucView® substrates are a gold standard for directly detecting caspase-3/7 activity in live cells.
How It Works When introduced to cells, the NucView® substrate is initially non-fluorescent and is able to penetrate the plasma membrane and enter the cytoplasm. During apoptosis, caspase-3/7 cleaves the substrate and releases the high-affinity DNA dye which leads to nuclear fluorescent staining that can be monitored in real-time.
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