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BLD pharm社 BLD Insights - Enzymatic Synthesis of Glycoside - Sugar Nucleotide

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June 2022 - Newsletter 17

BLD Insights

Enzymatic Synthesis of Glycoside - Sugar Nucleotide

  

Sugar nucleotide is formed by the combination of glycosyl and the terminal phosphate group of nucleoside monophosphate or diphosphate, which has important physiological significance. First, it acts as an intermediate in the transformation of monosaccharide structure. The second role is to serve as sugar donors in the biosynthesis of glycosides and polysaccharides. Compared to chemical glycosylation, enzymatic glycosylation can proceed stereo and regio-specifically in mild conditions without using protecting group manipulation procedures.

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