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Cytoskeleton社 Biologically Active Kinesin Proteins

   

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Motor Proteins from Cytoskeleton Inc.

Biologically Active Recombinant Proteins

  

Eukaryotic kinesin motor proteins utilize the energy of ATP hydrolysis to move cargoes, such as chromosomes and vesicles, along cytoskeletal microtubule networks. They play a major role in almost all aspects of intracellular transport and are involved in a wide range of physiological processes, including embryonic development, axonal transport, and cell division. 

 

Kinesin Heavy Chain Motor Domain Protein: GST Tagged (KR01)

 

Product Uses:

  • Measurement of microtubule-activated ATPase activity
  • Identification/characterization of proteins or small molecules that affect motor ATPase activity
  • Identification/characterization of proteins or small molecules that affect kinesin motility
  • Identification/characterization of proteins or small molecules that affect motor/microtubule interactions

 

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 KR01.jpgFigure Legend. Microtubule activated kinesin ATPase assay (Cat. # BK060) using kinesin heavy chain motor domain protein (Cat. # KR01) and pre-formed microtubules (Cat. # MT001). Each condition (microtubules (MT) alone, kinesin alone and microtubules + kinesin) was performed in triplicates.



  

 

Recent Citation

 

Jong-Wei Lin et al. Dexamethasone accelerates muscle regeneration by modulating kinesin-1-mediated focal adhesion signals. Cell Death Discov. 2021 Feb 17;7(1):35. doi: 10.1038/s41420-021-00412-4.

 

 

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Cytoskeleton's Motor Protein Tools:

Proteins - (Well characterized ATP analogs, perfect starting point to discover Kinensin ATPase inhibitors)

Kits - (Reliably measure ATPase activity, or characterize Kinesin inhibitors)

Drugs and Buffers - (Perfect for in vitro research on cytoskeletal components)

F-Actin Filaments - (<99% Pure, Highly Reliable and Reproduceable Results)

Microtubules - (Pre-formed Microtubules, enhance Kinesin hydrolysis)

 

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Check out a Recent Newsletter which focuses on Motors

 

Cytoskeleton prepared a newsletter on "Microtubules and Motor-Driven Cargo Delivery" Check it out by clicking the button below, or the image to the left!

 

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G-protein.gifSmall G-Protein Products Tubulin.gifTubulin Protein Products Actin.gifActin Protein Products

 

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www.cytoskeleton.com/activation-assays

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