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Cytoskeleton社 G-LISA and Pull-Down Activation Assays

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G-LISA and Pull-Down Activation Assays

The most trusted and cited activation assays available

About Our Activation Assays:

Cytoskeleton's Small G-protein Activation Assays measure the active, GTP-bound form of the protein from a cell or tissue extract.

  • Activation assays are available in two formats: the traditional pull-down bead format and our advanced ELISA based G-LISA format. 
  • Measure Arf1Cdc42RacRalRas, and Rho
  • Accurate, sensitive, and user-friendly formats
  • The most trusted and cited activation assays available

Watch our video or browse the options below to learn more about which format is right for you.

Cytomovie.pngAbove Video: Small GTPase Activation Assays - Choosing your Format


Recent Activation Assay Citation Spotlight and Newsletter


 The process of new blood vessel growth from the existing vasculature known as angiogenesis occurs in both health and disease as a mechanism to supply surrounding tissue with the necessary exchange of nutrients and metabolites. One of the key components in sprouting angiogenesis is the proliferation, migration, and signaling changes that occur in endothelial cells. The Notch signaling pathway has been identified as a key regulator to control angiogenesis, but the mechanisms are complex and not fully defined.

Click to Read the Citation

GTPase.jpgSmall GTPases, also known as small G-proteins, are a large family of regulatory factors with roles in virtually all cellular processes. They essentially act as molecular switches, adopting either GDP-bound inactive (“off”) or GTP-bound active (“on”) states, through structural changes induced by the presence or absence of the γ-phosphate group of GTP. In humans, the small GTPase family contains approximately 150 members, and is further classified into five subfamilies—Ras, Rho, Arf, Rab, and Ran—based on their sequence and structure.

Click to Read the Newsletter


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