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Three New Lipibright Lipid Droplet Probes

We are excited to announce our latest product Lipibright! These probes consists of bright, fluorogenic live cell dyes that stain lipid droplets. LipiBright™ probes fluoresce 300 to 1000 times brighter in an oily/lipid environment compared to aqueous solutions.

LipiBright probes are photostable and possess narrow absorption and emission bands, a distinct advantage over the traditional Nile Red probe; thus, multicolor imaging is possible. These probes exhibit ideal characteristics for microscopy and have been validated with multiple techniques including epifluorescent (widefield), confocal, and two photon.

Available in 3 Color Options

Above: Structure and range of fluorescence. A - Structure of LipiBright SMCy3.5, 5.5 and 7.0, note the increasing length of spacer between exciter and emitter portions. B - Normalized absorption spectra (blue) and normalized emission spectra (orange) of SMCy3.5, SMCy5.5 and SMCy7.5 in Labfrac oil. 

Other Spirochrome SiR and SPY™ Probes For Bioimaging
 

Live-cell imaging probes developed by Spirochrome are cell-permeable compounds which stain microtubules (SiR-Tubulin), F-actin (SiR-Actin), Lysosomes (SiR-Lysosome) and chromosomal DNA (SiR-DNA) in living cells. Also available: next generation live-cell SPY™ Probes, membrane tension FLIPPER-TR probes, and BG-Substrates from Spirochrome™.