Cytoskeleton社 New Tools: SPY700-FastAct™ For Dynamic Actin Visualization
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Spirochrome's Newest SPY-FastAct Probe Is Here!
Bright, Fluorogenic Dynamic F-actin Visualization
Spirochrome's latest probe, The SPY700-FastAct Probe, allows for bright and dynamic F-actin live cell imaging.
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The SPY700-FastAct (Cat # CY-SC605) advantage:
· Labels very fast actin dynamics
· SPY700-FastAct™ is based on our bright, photostable & far red SPY700 fluorophore which is far superior than fluorescent proteins
· Low toxicity
· Can be imaged with standard Cy5 filtersets but using a 700nm LP emission filter is best
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Above: SPY700-FastAct™ in HUVECS with SPY505-DNA and SPY595-DNA |
Advantage over other actin probes:
· No need for transfection or genetic manipulation
· Can be used for widefield, confocal, SIM or STED imaging
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Above: Emisson Spectra of SPY700-FastAct
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Other Spirochrome SiR and SPY™ Probes for Bioimaging
Live-cell imaging probes developed by Spirochrome are cell-permeable compounds which stain microtubules (SiR-Tubulin), F-actin (SiR-Actin), Lysosomes (SiR-Lysosome) and chromosomal DNA (SiR-DNA) in living cells. Also available: next generation live-cell SPY™ ™ Probes, membrane tension FLIPPER-TR probes, and BG-Substrates from Spirochrome™. |
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