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OriGene社 Hypoxia researchers win the 2019 Nobel Prize in medicine

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Hypoxia inducible factors (HIF)

- Scientists have won a 2019 Nobel Prize for the study of HIF

This Monday, three scientists have been awarded the Nobel Prize in Medicine for their work on the molecular switch that regulates cell response to oxygen level. The discovery of the central protein, HIF, has led to potential drug development for the treatment of anemia, cancer, and many other diseases.

OriGene offers high quality research products for various HIF subunits, their regulators and downstream target proteins.

Hypoxia researchers win the 2019 Nobel Prize in medicine.png

HIF subunits

HIF1A     Master regulator of hypoxia

HIF2A     Share high homology with HIF1A

HIF3A     Negative regulator on HIF1A or HIF2A  

HIF1B    Forms heterodimer with HIF1A and HIF2A

HIF regulators

HIF target genes

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