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OriGene社 Immuno-Checkpoints: Overview and Research Tools

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Immuno-Checkpoint Proteins: Overview & Research Tools

Interaction between immune checkpoint proteins such as PD-L1 and PD-1 found on surface of T cells interact resulting in T cell immune suppression but in cancer cells, this mechanism is suppressed leading to failure in detection of the abnormal cancer cells.

CTLA-4, PD-1, LAG-3, TIM-3, KIRs, and GITR are some of the major  immune checkpoint proteins. Learn about Immune checkpoint proteins and research tools

Immuno-Oncology Research Tools

Why expression hosts selection  is critical for recombinant human protein synthesis?
One of the challenges of studying  a protein is to get a large quantities that close to the native protein.  Proteins expressed in  human cells such as HEK293  demonstrate

  • Preservation of protein structure, post translational modifications, & functions
  • Ideal for antibody production
  • Studying protein-protein interaction

Learn more from this short video on 'Expression Hosts for Recombinant Proteins'

Interested in synthesizing custom proteins?  Ask for a quote

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