OriGene社 PD-L1 - A Promising Target for Cancer Therapies
PD-L1 (programmed death ligand-1), also known as CD274, through its ligation to PD-1, can limit the activity of T cells in peripheral tissues during pathogen infection to prevent autoimmune responses. This interaction is exploited by cancer cells to evade effector T-cells and maintain immune tolerance. Thus, the PD1-PD-L1 axis has been heavily targeted and several clinical trials have received promising results.
OriGene provides extensive tools for PD1-PD-L1 related studies. Try our application validated TrueMAB antibodies today.
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