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Tocris Bioscience社 2012年3月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
4432 TTP 22 High affinity, selective CK2 inhibitor
4486 PMSF Non-specific protease inhibitor; also blocks anandamide metabolism
4370 TC-N 22A Potent, selective mGlu4 positive allosteric modulator
4416 ADX 10059 hydrochloride Negative allosteric modulator at mGlu5
4357 Bicifadine hydrochloride Noradrenalin, 5-HT and dopamine re-uptake inhibitor
3357 Ellipticine Antitumor and intercalating agent; inhibits DNA topoisomerase II
3354 PF 429242 Competitive inhibitor of SREBP site 1 protease
4481 Ki 20227 c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
4474 20(S)-Hydroxycholesterol Allosteric activator of Hedgehog signaling; induces Smo accumulation
4458 VU 29 Potent mGlu5 allosteric potentiator
4371 VU 0364439 Positive allosteric modulator at mGlu4
4343 UNC 0638 Selective G9a and GLP histone lysine methyltransferase (HMTase) inhibitor
3988 Hesperadin hydrochloride Potent Aurora B kinase inhibitor
4469 VU 0364770 Positive allosteric modulator at mGlu4
4471 DMH4 Potent, selective VEGFR-2 inhibitor
4460 Trifluorothymidine Thymidylate synthase inhibitor; induces DNA fragmentation
4405 NVP BHG 712 Potent EphB4 kinase inhibito
4307 YC 1 Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest

                                                                                                                                                                                                      

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