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Tocris社 2012年5月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

       

Cat.No. Product Name Activity
4524 EGCG Inhibits formation of amyloid fibrils
4509 STF 083010 Inhibits IRE1α endonuclease activity
4505 ICG 001 Inhibits TCF/β-catenin-mediated transcription
4490 Alantolactone Antiproliferative; induces activin/SMAD3 signaling
3104 PU H71 Potent Hsp90 inhibitor
0898 Clocinnamox mesylate Irreversible µ antagonist
4535 Phalloidin Promotes actin polymerization
4496 BC 11-38 Selective PDE11 inhibitor
4431 A 1070722 Highly potent, selective GSK-3 inhibitor
4399 GNF 2 Selective allosteric inhibitor of Bcr-abl tyrosine kinase activity
4016 IDE 2 Induces definitive endoderm formation in mouse and human ESCs
1293 β-Lapachone DNA topoisomerase I inhibitor
4522 Flufenamic acid Cyclooxygenase inhibitor; NSAID. Also activates TRPC6
4520 Cytarabine Nucleoside analog; inhibits DNA replication
4479 4μ8C Inhibits IRE1 endoribonuclease activity
4451 IOX 2 Potent, selective HIF1α prolyl hydroxylase-2 (PHD2) inhibitor
4354 ML 130 Inhibits NOD1-induced NF-κB activation
4512 DMF Nrf2 pathway activator; neuroprotective
4511 MMF Activator of Nrf2 pathway; primary metabolite of DMF
4260 MRS 2957 triethylammonium salt Potent and selective P2Y6 agonist
2575 JMV 390-1 Inhibits multiple neurotensin and neuromedin N degrading enzymes
4502 DIM Induces apoptosis; inhibits EGFR activation
4501 Ribavirin Antiviral guanosine analog; blocks eIF4E activity
4498 Y 11 Potent and selective FAK inhibitor
4473 A 804598 Potent and selective P2X7 antagonist
4441 SEN 12333 α7 nAChR agonist; histamine H3 antagonist
4367 Psora 4 Potent KV1.3 channel blocker
4363 TC-SP 14 Potent S1P1 receptor agonist
4355 TC-F 2 Potent, reversible and selective FAAH inhibitor
3855 RuBi-Nicotine Caged nicotine; rapidly excitable by visible light
3333 NDT 9513727 Potent, selective human C5a receptor antagonist
                                                                                          

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