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Tocris社 2012年8月新製品

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 New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
4591 Deltorphin I Potent δ agonist
4620 Olmesartan medoxomil Selective non-peptide AT1 antagonist; prodrug of Olmesartan
4613 Tegaserod maleate 5-HT4 partial agonist
4590 Honokiol Blocks NF-κB activation. Displays anti-inflammatory and antioxidant properties
4583 Digoxin Na+, K+-ATPase inhibitor
4581 Grifolic acid Selective partial GPR120 agonist
4567 CCG 50014 Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4)
4318 BX 795 PDK1 inhibitor
4627 Phlorizin Na+-glucose cotransporter inhibitor
4617 Penitrem A Potent and selective BK channel blocker
4600 Auranofin Thioredoxin reductase inhibitor; induces MPT
4561 BIBN 4096 Potent and selective CGRP receptor antagonist
4539 (R)-(+)-Etomoxir sodium salt Carnitine palmitoyltransferase I (CPT1) inhibitor
2614 RWJ 56110 Selective PAR1 antagonist
4618 GW 6471 PPARα antagonist
4599 3,5-DHBA Selective HCA1 agonist
4579 Pentobarbital sodium salt Enhances GABAergic activity
4578 Phenobarbital sodium salt Enhances GABAergic activity
4577 LDV FITC Fluorescent ligand for α4β1 (VLA-4)
4570 ML 161 Inhibits PAR1-mediated platelet activation
4525 Piclamilast Potent and selective PDE4 inhibitor
4516 UNC 926 hydrochloride Binds the MBT domain of L3MBTL1 polycomb protein
4514 JW 55 Tankyrase inhibitor; inhibits canonical Wnt signaling
4457 YE 120 GPR35 agonist
4445 PFI 1 BET bromodomain inhibitor; inhibits BRD2 and BRD4
4529 Ciliobrevin A Hedgehog pathway antagonist; inhibits ciliogenesis
4423 CHIR 99021 Highly selective GSK-3 inhibitor
4326 PhiKan 083 p53 stabilizing agent
4549 ML 133 hydrochloride Kir2.x inhibitor
4517 NS 2028 Potent soluble guanylyl cyclase (sGC) inhibitor
 

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