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Tocris社 2013年1月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
4710 PF 06465469 Potent inhibitor of interleukin-2 inducible T cell kinase (ITK). Also inhibits BTK
4558 EMPA Highly potent and selective OX2 antagonist; brain penetrant
4544 YM 244769 Na+/Ca2+ exchange inhibitor (reverse mode); neuroprotective
4499 (+)-JQ1 Potent, selective BET bromodomain inhibitor; cell permeable
4470 EMD 281014 hydrochloride Selective 5-HT2A antagonist
4381 VU 0285683 Negative allosteric modulator at mGlu5
4740 Lithium carbonate Mood stabilizer; inhibits Na+/K+ ATPase pump activity
4733 P005091 USP7 inhibitor
4729 α-Spinasterol TRPV1 antagonist; displays in vivo activity
4662 SMANT hydrochloride Inhibits Smoothened (Smo) accumulation
4463 SR 8278 REV-ERBα antagonist
1532 10Z-Hymenialdisine Pan kinase inhibitor; potently inhibits MEK-1
4741 Gadolinium chloride Stretch-activated calcium channel blocker; calcium-sensing receptor agonist
4739 Cesium chloride Potassium channel blocker; neuroprotective
4736 WIN 18446 ALDH1a2 inhibitor
4735 Quetiapine hemifumarate 5-HT2/D2 antagonist; atypical antipsychotic
4725 Eptifibatide Glycoprotein IIa/IIIb inhibitor; inhibits platelet aggregation
4713 IQ 1 Enables Wnt/β-catenin-driven expansion of ESCs; prevents spontaneous differentiation
4666 UNC 1215 Potent and selective L3MBTL3 domain inhibitor; cell permeable
4601 TUG 891 Potent and selective GPR120 agonist
4555 HI TOPK 032 Selective T-LAK-cell-originated protein kinase (TOPK) inhibitor
4317 JNJ 10397049 Selective OX2 receptor antagonist
1225 TCPOBOP Constitutive androstane receptor (CAR) agonist

 

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