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Tocris社 2013年11月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

 

Cat.No. Product Name Activity
5075 Harmine Potent and selective Dyrk1A inhibitor
5034 1,9-Dideoxyforskolin Inactive analog of forskolin (Cat. No. 1099)
4995 Phortress Prodrug of the antitumor agent 5F 203
4989 Salirasib Ras inhibitor; also induces autophagy
4972 JIB 04 Pan Jumonji histone demethylase inhibitor; active in vivo
4836 AZ 628 Potent Raf kinase inhibitor
4788 NS 11021 Activator of BKCa (KCa1.1) channels
4612 URB 597 Potent and selective FAAH inhibitor
4487 (±)-AMG 487 CXCR3 antagonist; inhibits cell migration and metastasis
2962 6'-GNTI dihydrochloride Selective κ/δ opioid heterodimer receptor agonist
5064 LY 379268 disodium salt Sodium salt of LY 379268 (Cat. No. 2453); selective group II mGlu receptor agonist
5049 TC-E 5001 Tankyrase inhibitor
5047 PRT 4165 Inhibitor of Bmi1/Ring1A
5032 Talampanel Non-competitive AMPA/kainate antagonist
4672 SB 223412 Potent, selective non-peptide NK3 antagonist. Brain penetrant
3515 FK 228 Potent and selective class I histone deacetylase inhibitor; antitumor
1992 Nomifensine Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
4953 CHIR 99021 trihydrochloride Hydrochloride salt of CHIR 99021 (Cat. No. 4423); selective GSK-3 inhibitor
4895 ML 298 hydrochloride Selective PLD2 inhibitor
4797 Org 37684 5-HT2 agonist
4787 CPPHA Positive allosteric modulator at mGlu1 and mGlu5
5048 YZ9 PFKFB3 inhibitor; inhibits cell growth
5028 GMQ hydrochloride ASIC3 opener
4858 NSC 697923 Selective inhibitor of E2 ubiquitin-conjugating enzyme Ubc13-Uev1A
4840 KU 0060648 Dual DNA-PK and PI 3-K inhibitor
4478 GPBAR-A Bile acid receptor TGR5 (GPBA) agonist
4334 PSB 0777 ammonium salt Potent adenosine A2A agonist
 

 

 

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