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Tocris社 2013年2月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

                               

Cat.No. Product Name Activity
4799 Capecitabine Prodrug of 5-Fluorouracil (Cat. No. 3257). Inhibits DNA synthesis
4798 (S)-Duloxetine hydrochloride Potent 5-HT and NE reuptake inhibitor; also blocks dopamine reuptake
4786 PD 0332991 isethionate Potent, selective Cdk4/6 inhibitor; brain penetrant
4537 NCX 466 Cyclooxygenase-inhibiting nitric oxide donor
4754 AK 7 Selective SIRT2 inhibitor; brain penetrant
4674 CZC 24832 Selective inhibitor of PI 3-Kinase γ
4670 SB 611812 Urotensin-II (UT) antagonist; attenuates cardiac dysfunction
4365 TC-MCH 7c Selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist
3379 Phenamil Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels
4781 ANA 12 TrkB receptor antagonist
4761 Plumbagin Induces G2/M cell cycle arrest; anticancer
4731 KY 02111 Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
4717 Jervine Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo
4700 PU 02 Negative allosteric modulator of 5-HT3
4676 ARRY 520 trifluoroacetate Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
4554 GC 1 High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic
3380 Benzamil NCX inhibitor, Deg/ENaC channel blocker; amiloride (Cat. No. 0890) derivative
 

 

         

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