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Tocris社 2014年4月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
5135 Propidium iodide Red-fluorescent DNA stain; membrane impermeant to live cells
5106 GSK 2193874 Potent and selective TRPV4 inhibitor; orally active
5076 SZL P1-41 Selective Skp2 inhibitor; suppresses E3 ligase activity
4893 XL 388 Potent and selective mTOR inhibitor; antitumor
4604 PTIQ Potent MMP-3 expression inhibitor; neuroprotective
4557 GTS 21 dihydrochloride Partial agonist at α7 nAChR
5154 HNGF6A Humanin analog; increases insulin sensitivity
5145 AI-3 ARE activator; induces Nrf2-ARE-dependent transcription
4949 MaxiPost Positive channel modulator; exerts subtype-specific effects
5168 Rose Bengal Potent EAAT and VMAT inhibitor; cell permeable
5111 GSK 1838705 Potent and selective IR and IGF1R inhibitor; antitumor
4826 SUN 11602 Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
5167 Congo Red EAAT inhibitor; also an amyloid fibril-binding dye
5144 CFM 4 CARP-1 mimetic; proapoptotic
5119 Calcein AM Cell permeable compound which is hydrolyzed to become fluorescent in living cells
4766 SIB 1508Y maleate Potent agonist of α4β2, α2β4, α4β4 and α3β4 nACh receptors
4569 PS 1145 dihydrochloride Selective IKK inhibitor; orally active
5132 UNC 0642 Potent and selective G9a and GLP histone lysine methyltransferase inhibitor
5118 SynaptoRedTM C2  Fluorescent dye; stains synaptic vesicles
5072 PFI 3 Potent and selective SMARCA4 and polybromo 1 inhibitor; also inhibits SMARCA2
5065 NSC 319726 Reactivator of mutant p53
5035 AS 2034178 Selective FFA1 (GPR40) agonist
4969 LY 2389575 hydrochloride Selective negative allosteric modulator of mGlu3
4777 ML 277 Selective Kv7.1 (KCNQ1) potassium channel activator; augments IKs current
4763 Pyridostatin pentahydrochloride Stabilizes G-quadruplexes; inducing DNA damage and cell cycle arrest
4605 (±)-SLV 319 Potent and selective CB1 receptor antagonist

 

 

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