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Tocris社 2014年7月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
5254 FH 1 Enhances iPSC-derived hepatocyte differentiation and maturation
5223 Monensin sodium salt Sodium ionophore; antibacterial agent
5213 LL 37 Antimicrobial peptide derivative of human cathelicidin
5171 NBOH-2C-CN hydrochloride Potent and selective 5-HT2A agonist
5109 SB 743921 hydrochloride Potent kinesin spindle protein (KSP) inhibitor
5068 ITD 1 Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
5250 Ramipril Non-peptide, competitive angiotensin converting enzyme (ACE) inhibitor
5173 MS 436 Potent and selective BRD4 bromodomain inhibitor
5161 ML 154 Potent and selective neuropeptide S receptor (NPSR) antagonist
4767 WAY 316606 hydrochloride Secreted frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling
4734 TRC 051384 Inducer of heat shock protein Hsp70
5228 Urea  Used to solubilize and denature proteins
5227 Tricine Electrophoresis buffer
5226 Sodium phosphate monobasic Commonly used in biological assay buffers
5225 Ponceau S Staining Solution Stain used to detect protein bands after Western blotting
5224 MTT Reagent used in the measurement of cell proliferation
5222 Hematoxylin Dye used to stain cell nuclei
5221 Guanidine Hydrochloride Protein denaturant
5220 Glycerol Widely used in sample buffer preparation
5219 L-Glutathione Reduced Endogenous antioxidant
5218 Bromophenol Blue Dye used in gel loading buffers
5217 Bovine Serum Albumin Widely used blocking agent for ELISA and blotting
5216 BIS-TRIS  Commonly used buffering agent
5095 DBM 1285 dihydrochloride p38 MAPK inhibitor; anti-inflammatory
4993 NSC 624206  Ubiquitin-activating enzyme (E1) inhibitor
4169 KS 176 Selective BCRP inhibitor
4139 Aprotinin Competitive serine protease inhibitor
3177 Boric acid Widely used in buffers for electrophoresis
3166 Sodium dodecyl sulphate solution Detergent used in electrophoresis of proteins
3165 Polyoxyethylenesorbitan monolaurate Detergent used for protein extraction
3156 Dulbecco's PBS Buffered saline used in mammalian cell culture
3153 Sodium phosphate dibasic Commonly used in biological assay buffers
3150 Potassium phosphate monobasic Commonly used in biological assay buffers
5245 Ebselen Glutathione peroxidase mimic; peroxynitrite scavenger
5230 BRD 7552 PDX1 transcription factor inducer; increases insulin expression
5184 BDS I Potent and reversible Kv3.4 potassium channel blocker; neuroprotective
4745 LIMKi 3 Potent LIM kinase inhibitor; antitumor
4694 Ro 5-3335 Core binding factor inhibitor; attenuates hematopoiesis differentiation
4625 TC OT 39 Nonpeptide oxytocin and V2 receptor partial agonist; also a V1a receptor antagonist
5190 FRAX 486 Potent p21-activated kinase (PAK) inhibitor; brain penetrant and orally bioavailable
5179 TCID Selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor
5141 AZD 5582 dihydrochloride Dimeric Smac mimetic; potent IAP inhibitor
5033 2-MPPA Selective glutamate carboxypeptidase II (GCP II) inhibitor; orally bioavailable
4842 BIX 02189 Selective MEK5 and ERK5 inhibitor
4783 Lu AA 47070 Prodrug of a potent and selective adenosine A2A receptor antagonist
4750 TC Mps1 12 Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor; orally active
2472 Triacsin C Inhibitor of acyl-CoA synthetase

 

 

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