Fount of Information

Tocris社 2015年1月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
5273 Bengamide B Potent inhibitor of NF-κB activation
5131 NAB 2 Protects against α-synuclein toxicity; promotes Rsp5/Nedd4-dependent endosomal transport
4941 PKI 166 hydrochloride Potent EGFR-kinase inhibitor 
4793 CE3F4 Uncompetitive Epac1 inhibitor
5374 GLP-1 (7-37) Endogenous bioactive GLP-1 receptor ligand
5373 C34 TLR4 inhibitor
5337 ML 365 Potent and selective TASK-1 channel blocker
5326 CHR 6494 trifluoroacetate Potent and selective haspin kinase inhibitor
5321 PSNCBAM-1 CB1 receptor negative allosteric modulator
5271 UNC 3230 Potent and selective PIP5K1C inhibitor; antinociceptive
5000 FTIDC Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
4943 UNC 1999 Potent and selective EZH2/EZH1 histone lysine methyltransferase inhibitor
4827 Garcinol PCAF/p300 HAT inhibitor; anticancer
5400 (S)-PFI 2 hydrochloride Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
5384 TA 02 Induces cardiomyocyte differentiation from hESCs
5383 TA 01 Induces cardiomyocyte differentiation from hESCs
5345 ML 348 Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor
5331 CPI 203 BET bromodomain inhibitor; arrests cell cycle at G1 phase
5284 trans-ISRIB Integrated stress response (ISR) inhibitor
5197 Spautin 1 USP10 and USP13 inhibitor; inhibits autophagy
5108 TFC 007 Potent hematopoietic prostaglandin D synthase (H-PGDS) inhibitor
5080 TC-G 1003 High affinity somatostatin sst2 receptor agonist
5009 BMS 509744  Potent and selective ITK kinase inhibitor 
4695 Ischemin sodium salt CBP bromodomain inhibitor; cell permeable

 

 

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