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Tocris社 2015年2月新製品

 

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
5428 MRS 5698 High affinity and selective A3 adenosine receptor agonist
5427 D-Luciferin sodium salt Firefly luciferase substrate
5425 TGN 020 Aquaporin 4 (AQP4) channel blocker
5420 Benzbromarone TMEM16A/B calcium-activated chloride channel (CaCC) blocker
5397 A01 High affinity Smurf1 inhibitor; enhances BMP signaling
5358 Cariporide Selective NHE1 inhibitor; cardioprotective
5329 CKI 7 dihydrochloride CK1 inhibitor
5324 M8 B hydrochloride Potent and selective TRPM8 channel blocker
5319 ACT 462206 Potent, dual orexin receptor antagonist 
5318 AEE 788 Potent EGFR and VEGFR inhibitor
5288 R 268712 Potent and selective inhibitor of TGF-βRI
5149 CX 614 AMPAkine; positive allosteric modulator of AMPA
5412 TC AQP1 1 Aquaporin 1 (AQP1) channel blocker
5344 ML 349 Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor 
5153 ML 240 ATP-competitive inhibitor of p97 ATPase
5422 XL 184 Potent VEGFR inhibitor; also inhibits other RTKs
5385 GSK 5959 Potent and selective BRPF1 bromodomain inhibitor
5353 Gap19 Cx43 hemichannel blocker
5299 JNJ 47965567 Potent and selective P2X7 antagonist; brain penetrant
5279 IWP 12 Potent Porcn inhibitor; active in vivo
5243 TC-S 7009 High affinity and selective HIF-2α inhibitor
5052 TG 4-155 High affinity and selective EP2 receptor antagonist
4837 AZD 3988 Potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor
4624 TC-FPR 43 Potent FPR2 agonist 
4234 4BP-TQS Allosteric agonist at α7 nAChR
5399 BTB1 Selective and ATP-competitive Kif18A inhibitor
5376 Pregnenolone sulfate sodium salt NMDA Potentiator 
5371 Clemizole hydrochloride TRPC5 blocker; also H1 antagonist
5323 WDR5 0103 WDR5 antagonist
5269 T 5601640 Selective LIMK2 inhibitor; antitumor
5214 IWP 4 Potent inhibitor of Wnt/β-catenin signaling
5206 JJKK 048 Potent and selective monoacylglycerol lipase (MAGL) inhibitor
5121 3PO PFKFB3 inhibitor; antiangiogenic
5017 A 85380 dihydrochloride High affinity and selective α4β2 agonist
4905 UNC 2400 Negative control of UNC 1999 (Cat. No. 4904)

 

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