Fount of Information

Tocris社 2015年7月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
5607 GNF 7 Ras signaling inhibitor; inhibits Ack1 and GCK
5601 DMXAA mSTING agonist; induces antitumor immunological responses
5600 BA 1 Potent BRS-3 agonist; also NMBR and GRPR agonist
5594 Spadin Potent TREK-1 channel inhibitor
5306 KJ Pyr 9 High affinity Myc inhibitor
4831 NS 3861 α3β2 full agonist; also α3β4 partial agonist
4829 ML 239 Breast cancer stem cell inhibitor
1374 SB 215505 5-HT2B/2C antagonist
5603 (-)-JQ1 Inactive control for (+)-JQ1 (Cat. No. 4499)
5576 PFI 4 Potent and selective BRPF1 bromodomain inhibitor
5443 AM 6545 High affinity and selective CB1 antagonist
5571 Lei-Dab 7 Potent, selective KCa2.2 blocker
5554 IHR 1 Potent Smo antagonist
5489 XD 14 BET bromodomain inhibitor
5485 GlyH 101 Reversible, voltage-dependent CFTR chloride channel blocker
5470 QAQ dichloride Photoswitchable Nav, Kv and Cav channel blocker
5232 AZ 191 Potent DYRK1B inhibitor
5079 ABT 089 dihydrochloride High affinity and selective α4β2 partial agonist
4784 Edaglitazone Potent and selective PPARγ agonist; antidiabetic
5567 EPZ 004777 Highly potent DOT1L inhibitor
5511 Sucrose Disaccharide used in biological buffers
5507 Carbenicillin disodium salt Antibiotic; selection reagent for AMPR transformed cells
5505 Kanamycin sulfate Broad spectrum antibiotic
5498 AP 811 High affinity, selective NPR3 antagonist
5484 C 87 TNF-α inhibitor 
5462 AAQ chloride Photoswitchable Kv channel blocker
5456 Zosuquidar trihydrochloride High affinity P-gp inhibitor
5379 VU 0469650 hydrochloride Potent and selective negative allosteric modulator of mGlu1
5378 VU 0422288 Selective group III mGlu positive allosteric modulator
5368 Maritoclax Mcl-1 inhibitor; proapoptotic
5246 MRS 1477 TRPV1 positive allosteric modulator
5185 JTE 607 dihydrochloride Cytokine release inhibitor; anti-inflammatory
5129 TC-G 1005 Potent and selective TGR5 agonist
5124 PD 404182 High affinity inhibitor of KDO 8-P synthase; also DDAH1 inhibitor
4860 ML 193 Potent, selective GPR55 antagonist
4702 ETP 45658 Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR
4597 NS 8593 hydrochloride Selective KCa2 (SK) channel negative modulator; inhibits SK currents
4492 Cerestat Potent and noncompetitive NMDA receptor antagonist
4482 PR 619 Broad spectrum DUB inhibitor
3105 FK 409 NO donor

 

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