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Tocris社 2015年9月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
5679 N-Acetylpurinomycin Downregulates SnoN and Ski protein expression; promotes TGF-β signaling
5677 RFRP-1 (human) Potent NPFF receptor agonist
5636 GS 143 β-TrCP1 ligase inhibitor
5591 I-BRD9 Potent and selective BRD9 inhibitor
5588 UF 010 Class I HDAC inhibitor
5640 PF 06463922 High affinity and selective ALK and ROS1 inhibitor
5553 Sephin 1 Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
5546 NI 57 Potent and selective BRPF bromodomain inhibitor
5463 PA 1 dihydrochloride Photoswitchable ENaC blocker
5317 WWL 123 α/β-hydrolase domain 6 (ABHD6) inhibitor; antiepileptic
5229 ABP 688 High affinity human mGlu5 receptor antagonist
5674 GW 501516 Potent and selective PPARδ agonist
5545 BX 430 Selective P2X4 allosteric antagonist
5429 NG 25 TGF-β-activated kinase (TAK1) inhibitor
5349 Treprostinil Potent prostacyclin (PGI2) analog
3375 Dolastatin 10 trifluoroacetate Tubulin polymerization inhibitor
5612 18A HIV cell entry blocker
5604 MI 14 Potent and selective PI 4-kinase IIIβ inhibitor
5586 Yoda 1 Piezo1 channel activator
5566 DG 172 dihydrochloride Potent PPAR β/δ inverse agonist; promotes BMC differentiation
5492 BMS 566419 Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
5648 Hydroxychloroquine sulfate Autophagy inhibitor; also TLR9 inhibitor
5577 S4 High affinity and selective CAIX and CAXII inhibitor
5568 S 18886 Potent thromboxane A2 (TP) antagonist
5565 Tiplaxtinin Plasminogen activator inhibitor-1 (PAI-1) inhibitor
4726 CTA 056 ITK inhibitor
5659 AmmTX3 KV4 channel blocker
5617 AZD 1480 Potent and selective JAK2 inhibitor; antiangiogenic
5585 Balicatib Potent and selective cathepsin K inhibitor
5490 5J 4 CRAC channel blocker; anti-inflammatory
5438 NTRC 824 Potent and selective non-peptide NTS2 antagonist
5211 AM-TS23 DNA polymerase λ and β inhibitor

 

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