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Tocris社 2016年3月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
5796 Azoramide Unfolded protein response (UPR) modulator
5765 4-azido-N-ethyl-1,8-naphthalimide Click-activated fluorescent probe
5681 N106 Activator of SUMO-activating enzyme, E1 ligase
5301 BPTES Selective allosteric glutaminase (GLS1) inhibitor
5039 SR 144528 High affinity and selective CB2 inverse agonist
4568 CPYPP DOCK2-Rac1 interaction inhibitor
5668 VUF 11222 High affinity non-peptide CXCR3 agonist
5592 LCB 03-0110 dihydrochloride Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
5100 TC-T 6000 Potent equilibrative nucleoside transporter 4 (ENT4) inhibitor
5083 QO 58 Kv7 channel opener
4968 CCT 241533 dihydrochloride Potent Chk2 inhibitor
4180 Beraprost sodium Potent prostacyclin IP receptor agonist
5823 Ala-Gln Stable form of L-glutamine; commonly used in cell culture
5819 Bexarotene Potent and selective RXR agonist
5792 ProTx III Potent Nav1.7 blocker; analgesic
5646 EML 425 Reversible and non-competitive p300/CBP inhibitor
5790 PF 05175157 Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
5769 TM 5275 sodium salt Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable
5666 JNJ 63533054 Potent and selective GPR139 agonist
5665 IRAK1/4 Inhibitor I IRAK4 and IRAK1 inhibitor
5660 NVP CXCR2 20 Potent and selective CXCR2 antagonist
5557 Dianicline Selective α4β2 nAChR partial agonist
5798 Irbesartan Potent AT1 antagonist
5772 Sacubitril calcium Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
5759 SW 033291 High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
5694 GSK 2033 Potent LXR antagonist
5687 Centrinone High affinity and selective PLK4 inhibitor
5661 666-15 Potent and selective CREB inhibitor
5615 AZD 3147 Potent and selective dual mTORC1 and 2 inhibitor; orally bioavailable
4707 MI 2 dihydrochloride Menin-MLL interaction inhibitor

 

 

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