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Tocris社 2016年6月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

Cat.No. Product Name Activity
5929 BeKm 1 Potent and selective KV11.1 (hERG) channel blocker
5775 AZ 6102 Potent TNKS1/2 inhibitor
5773 Akti-1/2 Potent and selective dual Akt1 and 2 inhibitor
5693 VU 0409551 Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable
5667 YK 3-237 SIRT1 activator
5946 3',3'-cGAMP sodium salt STING agonist
5645 2',3'-cGAMP sodium salt Endogenous high affinity STING agonist
5639 PF 6274484 High affinity and potent covalent EGFR kinase inhibitor
5931 PF 05089771 Potent and selective Nav1.7 channel blocker
5766 A 971432 Potent and selective S1P5 agonist
5621 GLPG 0974 Potent FFA2 antagonist
5590 BI 9564 Potent and selective BRD9 and BRD7 inhibitor; orally active
5445 SM 324405 Potent TLR7 agonist
5941 OD1 Potent hNav1.4, rNav1.6 and rNav1.7 channel activator
5940 AdTx1 Selective, high affinity, non-competitive α1A adrenoceptor antagonist
5938 Mambalgin 1 Selective ASIC1a inhibitor; analgesic
5930 PBIT JARID1 (Jumonji AT-Rich Interactive Domain 1) inhibitor
5916 Canertinib dihydrochloride Potent EGFR kinase inhibitor
5869 CDN 1163 SERCA2 allosteric activator
5856 Ritonavir HIV-1 and HIV-2 protease inhibitor
5781 A 425619 Potent TRPV1 antagonist
5707 RA 839 Nrf2 activator; inhibits Nrf2/Keap1 interaction
5671 SB 332235 Potent CXCR2 antagonist
5937 A 779 Selective Mas receptor (Ang-(1-7) receptor) antagonist
5928 RS 09 TLR4 peptide agonist; acts as an adjuvant in vivo
5852 Acetyl Pepstatin High affinity aspartic protease inhibitor; inhibits HIV-1/2 proteinases
5837 [Pro3]-GIP (Rat) High affinity rat GIP receptor partial agonist
5800 CHMFL-FLT3-122 Potent and selective FLT3 inhibitor
5838 [Pro3]-GIP (Mouse) GIP receptor antagonist
5774 DEL 22379 ERK dimerization inhibitor
5722 Ogerin Selective positive allosteric modulator at GPR68
5464 AC 4 Photoswitchable TRPV1 channel blocker
4503 CC 0651 Allosteric inhibitor of hCdc34

 

 

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