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Tocris社 2016年8月新製品

 

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

Cat.No. Product Name Activity
6007 INCB 024360-analog Potent indoleamine 2,3-dioxygenase (IDO) inhibitor 
5905 Neurosensor 521 Selective noradrenalin and dopamine fluorescent indicator
5744 NVS-CECR2-1 Potent and selective inhibitor of cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor 
5994 Enzastaurin Potent PKCβ inhibitor
5964 SI-2 hydrochloride Steroid receptor coactivator 3 (SRC-3) inhibitor
5961 HIOC Selective TrkB receptor agonist; neuroprotectant
5960 TMI 1 Adam 17 (TACE) and MMP inhibitor; orally bioavailable
5935 H2DCFDA Fluorescent ROS indicator; cell permeable
5870 Cilengitide Potent and selective inhibitor of integrins αvβ3 and αvβ5
5802 A37 ALDH1A1 inhibitor
5654 BMS 265246 Potent cdk1/2 inhibitor
5244 TC-E 5008 Selective mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor; phenotypically lethal
5166 Perhexiline maleate Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor
5979 Eicosapentaenoic Acid Endogenous polyunsaturated fatty acid; stimulates ERK1/2 phosphorylation
5959 Autocamtide-2-related inhibitory peptide, myristoylated CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide
5953 Adaptaquin HIF-prolyl hydroxylase-2 (PHD2) inhibitor; antioxidant
5868 SR 0987 T cell-specific RORγ (RORγt) agonist
5757 Tariquidar dihydrochloride Potent P-glycoprotein (P-gp) inhibitor
4862 PPTN hydrochloride High affinity and selective P2Y14 antagonist
5981 Itraconazole SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
4397 AV 412 Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinases

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