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Tocris社 2017年1月新製品

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New products are an essential component of our range. Introductions are made on an ongoing basis, with hundreds of new small molecules, peptides and antibodies being added every year. Our aim is to find the latest, otherwise unobtainable research tools, and bring them to the market as quickly as we can.

 

 

 

Cat.No. Product Name Activity
6159 4,9-Anhydrotetrodotoxin Potent and selective Nav1.6 channel blocker
6137 8-Cyclopentyl-1,3-dimethylxanthine  High affinity adenosine A1 receptor antagonist
6131 (R)-Modafinil Dopamine uptake inhibitor
6034 AM 2394 Potent glucokinase activator; orally bioavailable
5993 CP 673451 Potent and selective PDGFR inhibitor
5955 eCF 309 Potent mTOR inhibitor
5692 ITH 12575 Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor.
5518 UMB 68 GHB receptor ligand
6124 (R)-2-Hydroxyglutaric acid disodium salt KDM4A inhibitor; also NF-κB activator 
6117 CORM 2 Carbon monoxide-releasing molecule
6108 Galeterone CYP17 inhibitor; also androgen receptor antagonist 
6085 AZD 1283 High affinity P2Y12 antagonist 
6077 DETA NONOate Nitric oxide donor
6056 GSK 1363089 Potent inhibitor of MET, VEGFR2, Ron and AXL
6008 TP 064 Potent and selective PRMT 4 inhibitor
6005 PF 3758309 dihydrochloride Potent PAK4 inhibitor; orally available
5999 TP 472N Negative control for TP 472 (Cat. No. 6000)
5934 NCT 501 hydrochloride Potent and selective ALDH1A1 inhibitor
5833 Ex 26 Selective S1P1 receptor antagonist
5632 AZ Dyrk1B 33 Potent DYRK1B kinase inhibitor 
6112 (S)-Norketamine hydrochloride NMDA receptor modulator; analgesic
6095 2S,6S-Hydroxynorketamine hydrochloride Potent AMPA agonist; antidepressant 
6094 2R,6R-Hydroxynorketamine hydrochloride Potent AMPA agonist; lacks ketamine-related side effects
5996 (R)-Norketamine hydrochloride MDA receptor modulator; analgesic
5966 ML 233 Non-peptide apelin receptor agonist 
4991 HaXS8 Chemical dimerizer
6115 PF 06273340 Potent and selective pan-Trk inhibitor; peripherally restricted
6114 PF 06409577 Potent and selective allosteric activator of AMPK
6063 CCF 642 Protein disulfide isomerase (PDI) inhibitor
6014 Org 48762-0 Selective p38α/β inhibitor; orally bioavailable
5978 WL 47 - dimer High affinity caveolin-1 ligand

 

 

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