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Tocris Bioscience社 Exclusive! BromoTag(R) Degrader for Target Exploration and Validation




BromoTag® AGB1 is our new TAG Degrader licensed exclusively to Bio-Techne by the University of Dundee. TAG Degraders are valuable tools for validating targets and use a targeted protein degradation approach that is generalizable to any intracellular target protein.

To facilitate your experiments, we also offer the negative control (BromoTAG cis-AGB1, Cat. No. 7687) and the antibody for detection of BromoTag AGB1-induced degradation of fusion proteins.


Learn More About

BromoTag AGB1

Key Features of BromoTag® AGB1

  • Highly selective and potent "Bump & Hole" TAG Degrader (DC50, 6h < 15nM)
  • Recruits VHL to selectively degrade proteins tagged with the mutant BromoTag domain, Brd4BD2 L387A
  • Suitable for in vitro and in vivo applications

Hear From The Inventors

Watch our webinar to learn about the development of BromoTag. This Symposium also includes presentations from other leading scientists around hot topics in TPD research. 


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