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Tocris社 DCZ - New DREADD Ligand for In Vivo Electrophysiology

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New to the Tocris catalog, DCZ (Deschloroclozapine; Cat. No. 7193) is a highly potent hM3Dq and hM4Di DREADD agonist. This DREADD ligand displays superior specificity and blood brain barrier penetration, making it an excellent option for in vivo electrophysiology experiments.
 
Scroll down to find out more about this product, and check out new additions to our DREADD ligand range that will be coming soon!

 

 

Read the publication from Nature Neuroscience: Nagai et al (2020) Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys. Nat.Neurosci. 23, 1157 PMID: 3263228686.

DREADD Ligands Available & Coming Soon

Product Name

Cat. No.

Target

Coming Soon!

JHU 37152

7197

hM3Dq and hM4Di   DREADDs

Coming Soon!

JHU 37160

7198

hM3Dq and hM4Di   DREADDs

Available 

CNO (Water-soluble)

6329

hM3Dq and hM4Di   DREADDs

Available

DREADD agonist 21 (Water-soluble)

6422

hM3Dq and hM4Di   DREADDs

Available

Salvinorin B

5611

κ-opioid DREADD (KORD)

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Chemogenetics Research Bulletin

Want to know more about the development of DREADDs and DREADD Ligands, and their ion channel alternatives, PSAMs/PSEMS?
 
Then request your copy of our Chemogenetics Research Bulletin!
 
Request Copy

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