Tocris Bioscience社 DCZ - New DREADD Ligand for In Vivo Electrophysiology

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New to the Tocris catalog, DCZ (Deschloroclozapine; Cat. No. 7193) is a highly potent hM3Dq and hM4Di DREADD agonist. This DREADD ligand displays superior specificity and blood brain barrier penetration, making it an excellent option for in vivo electrophysiology experiments.

Scroll down to find out more about this product, and check out new additions to our DREADD ligand range that will be coming soon!

Find Out More

Read the publication from Nature Neuroscience: Nagai et al (2020) Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys. Nat.Neurosci. 23, 1157 PMID: 3263228686.

DREADD Ligands Available & Coming Soon

	Product Name	Cat. No.	Target
Coming Soon!	JHU 37152	7197	hM₃D_q and hM₄D_i DREADDs
Coming Soon!	JHU 37160	7198	hM₃D_q and hM₄D_i DREADDs
Available	CNO (Water-soluble)	6329	hM₃D_q and hM₄D_i DREADDs
Available	DREADD agonist 21 (Water-soluble)	6422	hM₃D_q and hM₄D_i DREADDs
Available	Salvinorin B	5611	κ-opioid DREADD (KORD)

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Chemogenetics Research Bulletin

Want to know more about the development of DREADDs and DREADD Ligands, and their ion channel alternatives, PSAMs/PSEMS?

Then request your copy of our Chemogenetics Research Bulletin!

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