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Tocris社 PROTAC ® panel builder and chemical building blocks

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Your Trusted Supplier of Innovative and High-Performance Life Science ReagentsPROTAC_panel_builder_and_chemical_building_blocks_2.png

Are you working on Degrader (PROTAC ®) development? Well, we have just made it easier for you with our new PROTAC® Panel Builder online tool.

Select your preferred:

  • E3 ligase ligands & exit vectors (targeting VHL, Cereblon or IAP)
  • Linkers (PEG or alkyl chains of variable length)
  • Functional groups to couple to your target ligand of interest

and we will send you a quote for your chosen panel of Degrader building blocks.

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Degrader Building Blocks

Did you know that Tocris supplies a wide range of off-the-shelf functionalized building blocks to support your Degrader development program? Our building blocks comprise the most effective and commonly used E3 ligase ligands, functionalized at positions known not to interfere with binding affinity, and conjugated to common linker groups.

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Developing Degraders Scientific Poster

Authored by our in-house experts this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed.

Download Your Copy

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