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Check out this month’s new product introductions from Tocris Bioscience. See below for a selection of our innovative new product releases or visit our website for the complete list. 

 

Product Name Research Area/ Application Target Action
Kyoto Probe-1 Fluorescence Imaging iPS/ES cells Monitors pluripotency
LC 2 Cancer/ Targeted Protein Degradation KRAS Degrader
FNIR-Tag, NHS Fluorescence Imaging Labeling antibodies/ proteins Near-infrared fluorescent dye
SIM1 Cancer/Targeted Protein Degradation BET bromodomains Degrader
Rf470DL Fluorescence Imaging Peptidoglycans in live bacteria Blue
rotor-fluorogenic fluorescent
D-amino acid

 

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Blog Post: Development of a
KRAS-Targeting PROTAC®

In this new blog post, Michael Bond (Yale University) discusses the design of LC 2, a first-in-class KRAS G12C-targeting PROTAC now available from Tocris. Learn about the rationale behind the design of this new small molecule Degrader and why we need a larger toolbox of E3 ligase ligands.

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PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

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