Dear Researcher,
SARS-CoV-2 binds to the ACE2 (Angiotensin-converting enzyme) receptor to gain entry into host cells. ACE2 is expressed in many cell types and tissues including heart, blood vessels, liver, kidney, and pulmonary alveolar cells. Evidence for a protective effect of ACE inhibitors in patients with COVID-19 was shown in a recent study by Hongliang Li et al. In this newsletter, we are showcasing some of our featured ACE2 related products which might be helpful in the R&D of antiviral therapies and can be an essential tool to aid the researchers.

We hope that you find this newsletter to be a valuable source of information.

        ACE Inhibitors

Lotensin

Catalog No: B119750

• A prodrug of the ACE inhibitor benazeprilat
• Used to treat hypertension, congestive heart failure, and chronic kidney diseases

Perindopril t-Butylamine Salt

Catalog No: P287505

• An ACE inhibitor and antihypertensive
• Synonyms: Perinodopril; Perinodpril Erbimune; Prestarium; Procaptan; S 9490-3; Perindopril Erbumine USP

Spinorphin

^{Catalog No: S681958} 

• Spinorphin is a novel neuropeptide, which exhibits complete inhibition of agonist-induced nociception
• Inhibits enkephalin-degrading and angiotensin-converting enzymes

         Labelled ACE Inhibitors 

Captopril-d3

Catalog No: C175752

• Labelled orally active angiotensin-converting enzyme (ACE) inhibitor.

Benazepril-d5

Catalog No: B119752

• Labelled Benazepril, which is used as an antihypertensive.https://www.trc-canada.com/product-detail/?B119752