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RESEARCH NEWS

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It’s Prime Time for mRNA in Cancer Immunotherapy Research


In our most recent edition of our Zon blog we're looking at four examples of general strategies directed at treating cancer which collectively accounted for 10 million deaths in 2020 alone: Shared Tumor Antigens, Neoantigens, Immunostimulants and Chimeric Antigen Receptor T Cells. 

 

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Milli-injector Capsules Enable Dosing of Nucleic Acids

 

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TwinPE: A Novel Method for Gene Editing Without Double-strand DNA Breaks

Nucleic acid therapeutics and vaccines hold vast potential for treating and preventing a broad range of diseases. However, their utility is currently limited by the need for injectable delivery. Learn more about how orally dosed mRNA nanoparticles could be applicable for human use in our Research Spotlight.

 

This Research Spotlight highlights a novel method for gene editing without double-strand DNA breaks: TwinPE. Unlike other targeted approaches, it uses a prime editor protein and two prime editing guide RNAs for programmable deletion, substitution, insertion, or inversion of larger DNA sequences.

 

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UPCOMING EVENTS

 

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TriLink Workshop @ RNA Leaders World Congress in Basel

Already, mRNA-related research is filling pipelines, and manufacturers are looking for efficient ways to make it on a large scale and for clinical-grade applications. However, the processes involved rely on highly technical expertise, limited materials, and accredited facilities. To that end, a vital component of mRNA-based vaccine and therapeutic development efforts is making informed decisions about manufacturing partnerships early.


Join us in this interactive workshop at the RNA Leaders World Congress to learn about innovative solutions for mRNA production. Don’t miss the opportunity to see what a path to partnership that scales with you at every stage of development looks like.

 

TriLink Workshop: Thursday March 17, 2022, 2pm (CET)

                                Thursday March 17, 2022, 10pm (JST)

 

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