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RESEARCH NEWS

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Exosomes Advance from Biological Curiosities to Clinical Applications


This blog highlights two recent examples of mRNA delivery mediated by exosomes for future therapeutic applications: Exosome-based mRNA therapy for treating familial hypercholesterolemia; and exosome-mediated mRNA delivery to induce SARS-CoV-2 immunity. Both reports provide compelling evidence for performing additional studies on the clinical utility of exosomes for mRNA delivery.

 

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Mobilization could replace chemotherapy during treatment with gene-edited stem cells

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Dual antigen self-amplifying RNA vaccines promise enhanced protection against SARS-CoV-2

Mobilization promises to replace chemotherapy as a means of bone marrow depletion, improving the lives of patients undergoing hematopoietic stem/progenitor cell gene therapy (HSPC-GT). Find out more in our recent research spotlight.​​​​

 

 

​​​​​A dual-antigen self-amplifying RNA vaccine has been shown to induce potent humoral and cellular immune responses that offer protection against emerging variants of SARS-CoV-2. Read on to learn more about the advantages of saRNA vaccines and why accelerating their development is important.

 

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UPCOMING EVENTS

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Influenza mRNA Vaccines: Mechanisms and Methodologies

 

In this first-of-the-series webinar, which GEN and The CRISPR Journal are co-hosting, our distinguished speaker will be Dr. Norbert Pardi, who has been doing some excellent, cutting-edge work on the development of broadly protective mRNA-based influenza vaccines. Not only will he discuss the mechanism of action of mRNA vaccines, Dr. Pardi will also tell us how his laboratory utilized a lipid nanoparticle-encapsulated, nucleoside-modified mRNA vaccine platform to deliver a combination of conserved influenza virus antigens.

 

Friday July 22, 2022, 11 a.m. ET

Saturday July 23, 2022, 0 a.m. JST

 

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2nd mRNA-Based Therapeutics Summit USA

 

The most anticipated event of the mRNA calendar, the mRNA-Based Therapeutics Summit is returning for its second year Jul 26 - Jul 28 as the comprehensive, industry-leading meeting for mRNA experts; your one-stop-shop for all your mRNA-based vaccine and therapeutic needs.

You can find TriLink at booth #9.

Join us for a presentation from one of TriLink’s Quality experts.

Quality Attributes to Support the Development of mRNA
Khaled Yamout
Senior Director, Manufacturing & Quality Control
TriLink BioTechnologies

 

Wednesday July 27, 2022, 2 p.m. ET

Thursday July 28, 2022, 3 a.m. JST

 

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