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RESEARCH NEWS
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| 3 Jab-Free Delivery Modes for mRNA Vaccines and Immunotherapeutics |
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Intramuscular injection, commonly referred to as the “jab,” is widely used to deliver vaccines and, currently, is the only route of administration of COVID-19 vaccines. In our most recent Zone In With Zon blog we are discussing the 3 jab-free delivery modes for mRNA vaccines and Immunotherapeutics.
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IL-1 and IL-1ra Regulate the Inflammatory Response to RNA Vaccines
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In Vivo of CAR T Cells Promises to Treat Cardiac Injury
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With RNA vaccines seeing increased use following successes in protecting against COVID-19, elucidating the underlying mechanisms of action is essential to maximize their potential. Read about how IL-1 and IL-1ra can regulate the inflammatory response to RNA vaccines.
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In many chronic heart diseases, activated fibroblasts fail to quiesce and instead continue secreting extracellular matrix, which can lead to fibrosis. To address this risk, researchers have developed a method for transiently producing functional antifibrotic CAR T cells in vivo using lipid nanoparticle (LNP) mRNA technology.
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