Column Image

  • Cyanopropyl group bonded stationary phase
  • Enables separation of different hydrophobic samples without using gradient
  • For separation of natural compounds with different hydrophobicity

Product Information

Column Specifications

Column Specifications

Rapid Analysis

Gradient elution is commonly used for the samples containing both polar and non-polar compounds. However, gradient elution may cause reproducibility problem depending on the gradient mixer and pump, and need an equilibration time for each analysis. COSMOSIL 5CN-MS offers rapid analysis and great reproducibility using isocratic elution mode.


Flow Rate 1.0 ml/min Sample
  1. Theobromine
  2. Theophylline
  3. Caffeine
  4. Benzene
  5. Toluene
Temperature 30°C
Detection UV 254 nm
Small hydrophobicity Structure
Large hydrophobicity Structure




Column Size 4.6 mm I.D. x 150 mm Sample
  1. p-Aminophenol (0.2 µg)
  2. p-Acetamidophenol (0.2 µg)
  3. 4'-Acetoxyacetanilide (0.2 µg)
Mobile Phase Methanol/ 50mmol/l KH2PO4 (pH4.7 with NaOH) = 20/80
Flow Rate 1.0 ml/min
Temperature 30°C
Detection UV 225 nm

Ordering Information

Analytical and Preparative Column (Particle size : 5 µm)

COSMOSIL 5CN-MS Packed Column

Product Name Size Product No. Price
COSMOSIL 5CN-MS Guard Column
4.6 mm I.D. x 10 mm 38231-81 e-Nacalai
10 mm I.D. x 20 mm 38232-71
COSMOSIL 5CN-MS Packed Column
4.6 mm I.D. x 50 mm 38233-61 e-Nacalai
4.6 mm I.D. x 100 mm 38234-51
4.6 mm I.D. x 150 mm 38235-41
4.6 mm I.D. x 250 mm 38236-31
6.0 mm I.D. x 150 mm 38237-21
6.0 mm I.D. x 250 mm 38238-11
10 mm I.D. x 250 mm 38239-01
20 mm I.D. x 250 mm 38240-61

(Storage) RT: Room temperature, A: Cool and dark, R: Refrigerator, F: Freeze